Endocrine Abstracts

Background: The diabetes type 1 (DM1) is a chronic autoimmune disease, it tends to appear in childhood, its incidence continues to rise and the complications arising from improper care poses serious health problems for those who suffer. LADA diabetes is autoimmune diabetes which appear in adults.Objetive: To describe the characteristics of the new diabetes debut in our environment.Material and methods: We included all patients who ...

Background: In last year, different analogues of very long duration basal insulin have appeared, which favors the flexibility in its use. Both ensure a decrease in the rate of hypoglycemia and improve glycemic control in clinical trials. However, in real practice we have few data in real practice.Objective: To compare the two ultralente insulin analogues in real practice. To analyze if they are cost effective.Material and methods: ...

Objective: Transsphenoidal surgery (TSS) presents the treatment of choice for Cushing’s disease (CD), 95% microadenomas. Remission and recurrence rates vary dependent on tumor size, extension, adenoma visibility on magnetic resonance imaging, and neurosurgical expertise. Remission rates in the postoperative vary between 55 and 85%, with a recurrence of up to 25%. The aim of this study was to describe the rate of remission and recurrence of CD in our midst after TSS, and c...

Introduction: Bariatric surgery has important metabolic complications such as bone mass loss.Goal: To assess bone mineral density (BMD) after Roux-en-Y gastric by-pass (RYGB) in patients under standard calcium and vitamin D supplementation.Method: In patients with morbid obesity submitted to RYGB, we measured BMD with a dual X-ray densitometer. Using World Health Organization (WHO) criteria’s, values were compared with young c...

Introduction: Thyroid nodules are very common in the general population (20–75% ultrasound). There are clinical management criteria established by international societies and standardized cytological diagnostic criteria (Bethesda). However, there is still uncertainty in the management of category 3 (follicular lesion of undetermined significance). Objectives: To evaluate the clinical attitude to the cytological diagnosis of Bethesda category 3 (B3) in thyroid fine-needle ...

Background: Acromegaly is the consequence of excessive growth hormone (GH) secretion, usually produced by a pituitary adenoma. In the last years, statins have been implicated in the response to treatment of patients with acromegaly. Although this fact is not very clear.Objective: To analyze whether pretreatment with statins modifies the adenoma molecular phenotype of the acromegalic patients and how this changes could help to influence the response to tr...

Objective: The aim of this study was to assess the utility of arterial calcium stimulation with hepatic venous sampling (ASVS) in the localization of tumors in patients with endogenous hyperinsulinism not detected with other methods.Patients and methods: We performed a retrospective study of 30 patients admitted to our hospital for hypoglycemia who underwent ASVS because the source of hyperinsulinism was not clearly identified by other imaging techniques...

Introduction: In type 2 diabetes the choice of the second drug after metformina is marked by the basic characteristics of the patient.Objetive: To analyze in real clinical practice the effectiveness of different antidiabetics.Material and methods: Observational study including patients with type 2 diabetes, in which we added to metformina different antidiabetics. We revised them 3-6 months from change.Results...

Background: Cushing’s syndrome (CS) is considered to be more frequent among patients with metabolic syndrome. Previous studies have suggested to perform a routine screening for CS in obese patients; however, more recent reports only recommend a case-finding approach in patients with uncontrolled diabetes and hypertension, despite appropriate treatment.Objective: The aim of this study was to evaluate the prevalence of unsuspected CS in morbidly obese...

Introduction: Recent studies defend the measurements of insulin resistance and β-cell function to assess the endocrine pancreatic function in patients with cystic fibrosis (CF). HOMA-IR indexes greater than 1 translate insulin resistance and HOMA-%β values lower than 100% imply an altered β-cell function.Aim: To describe insulin resistance and β-cell function using HOMA-IR and HOMA-%β indexes in patients with CF and compare them ...